Investigating the Synergistic Role of GCN2 and HPA Axis in Regulating Integrated Stress Response in the Central Circadian Timing System
Yannuo Li, Lingjun Lu, Jordan L. Levy, Tracy Gautsch Anthony, Ioannis P. Androulakis
This study investigates the interaction between the circadian system and integrated stress response through a mathematical model, showing GCN2's role in linking ISR with circadian rhythms and its impact on re-entrainment after jetlag.
bioRxiv · Feb 1, 2024 · PreprintSystems Biology