Shear Difference: Flow Type Dictates Endothelial Flow-Responsive Gene Programs in a 3D-Printed in vitro Model
Nasir Shah, Kerry‐Anne Rye, Zoltan Huba Endre, Tracie Jacqueline Barber, Jonathan Erlich, Blake J. Cochran
This study shows that pulsatile and continuous flow in a 3D-printed model lead to distinct endothelial cell morphology and transcriptional responses, highlighting flow type's impact on vascular function and disease.
bioRxiv · Nov 24, 2025 · PreprintBioengineering