Author

Zhiya Lu

Sun Yat-sen UniversityORCID 0000-0002-6595-0563Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:gene regulatory network inference· 1 Assay:whole-exome sequencing· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Bingxi LeiiD· 1 shared D.N. CooperiD· 1 shared Dan HeiD· 1 shared Feiyi LiuiD· 1 shared Huasong ZhangiD· 1 shared Huiying ZhaoiD· 1 shared Ling LiiD· 1 shared Mengbiao GuoiD· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperBioinformatics

Bingxi LeiORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Integrating gene mutation spectra from tumors and the general population with gene expression topological networks to identify novel cancer driver genes

Dan He, Ling Li, Zhiya Lu, Shaoying Li, Tianjun Lan, Feiyi Liu, Huasong Zhang, Bingxi Lei, D.N. Cooper, Huiying Zhao

DGAT-cancer integrates mutation spectra and gene expression networks to identify 571 novel cancer drivers, with EEF1A1 validated as a glioma driver.

bioRxiv · May 2, 2023 · PreprintBioinformatics

Enhancer RNA-based modeling of adverse events and objective responses of immunotherapy

Mengbiao Guo, Zhiya Lu, Yuanyan Xiong

This study predicts immune-related adverse events and objective response rates to anti-PD-1/PD-L1 therapy using enhancer RNA expression, identifying key regulatory genes involved in immune responses.

bioRxiv · Dec 16, 2021 · PreprintBioinformatics