Mengbiao Guo

The paper identifies silencer-linked RNAs in leukemia, showing they hijack FOXP1 to enhance MYC oncogene expression and promote cancer progression.

The paper develops a computational framework to analyze RNA editing in cancer, identifying functions and biomarkers for immunotherapy.

The paper identifies disease genes and pathways in systemic lupus erythematosus by analyzing DNA methylation differences in blood cells, finding distinct patterns in T and B cells.

The paper reanalyzes CRISPR-Cas9 data to show p53-dependent sex bias in cancer cell lines, highlighting genes and factors involved in this effect.

This study predicts immune-related adverse events and objective response rates to anti-PD-1/PD-L1 therapy using enhancer RNA expression, identifying key regulatory genes involved in immune responses.

This study identifies 38 novel SLE loci and shows genetic heterogeneity across ancestral groups, highlighting antibody production as a potential mechanism for disease disparities.

RETA is an R package that simplifies whole exome and targeted region sequencing data analysis by providing a comprehensive, interactive report with advanced visualization tools.