Benchmarking of duplex sequencing approaches to reveal somatic mutation landscapes
Yang Zhang, Vinay Viswanadham, Michail Andreopoulos, Dominik Głodzik, Ruolin Liu, Lovelace J. Luquette, Se‐Young Jo, Azeet Narayan, Muchun Niu, Lisa Anderson, Joseph Brew, Hsu Chao, Carrie Cibulskis, Guanlan Dong, Uday S. Evani, , Tim H. H. Coorens
This study benchmarks six duplex sequencing technologies to evaluate their performance in detecting somatic mutations across different genomic contexts and tissue types.
bioRxiv · Dec 15, 2025 · PreprintGenomics