GenomicsbioRxivPreprint
Incorporating FDR into the assessment of nanopore sequencing for the reliable detection of DNA modifications in real applications
Yimeng Kong, Hao Chen, Edward A. Mead…·Gang Fang
This paper introduces modFDR, a framework to assess nanopore sequencing for DNA modification detection, showing it reliably detects abundant modifications but has high false positives for rare ones.