Author

Jagadish Chandrabose Sundaramurthi

The Jackson Laboratory for Genomic MedicineORCID 0000-0002-6670-9157Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Genetic & Genomic Medicine· 3 Bioinformatics· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:differential expression· 3 Approach:statistical model· 3 Research Focus:database / resource· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Peter N. RobinsoniD· 4 shared Chris MungalliD· 3 shared Damian P. SmedleyiD· 3 shared Daniel DanisiD· 3 shared Julius O.B. JacobseniD· 3 shared Leigh CarmodyiD· 3 shared Adam S.L. GraefeiD· 2 shared Justin ReeseiD· 2 shared

Activity by Year

2017-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersGenetic & Genomic Medicine

Peter N. RobinsonORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A Phenotypic Paradigm for Cerebral Palsy Genetics

Adam S. Arterbery, Michael A. Gargano, Anita M Bagley, Jagadish Chandrabose Sundaramurthi, Lauren Rekerle, Thania Ordaz‐Robles, Daniel Danis, Adam S.L. Graefe, Ana Laura Arenas-Díaz, Jeremy Bauer, Hannah Blau, Leigh Carmody, Kristen L. Carroll, Janice Davis, Philip F. Giampietro, , Peter N. Robinson

The paper identifies pathogenic variants in 15.8% of CP patients and finds only 16 of 60 genes have significant CP association.

The American Journal of Human Genetics · Sep 1, 2026Peer-reviewedGenetic & Genomic Medicine

A corpus of GA4GH Phenopackets: case-level phenotyping for genomic diagnostics and discovery

Daniel Daniš, Michael J Bamshad, Yasemin Bridges, Andrés Caballero-Oteyza, Pilar Cacheiro, Leigh Carmody, Leonardo Chimirri, Jessica X. Chong, Ben D Coleman, Raymond W. M. Dalgleish, Peter Freeman, Adam S L Graefe, Tudor Groza, Peter Hansen, Julius O.B. Jacobsen, , Peter N. Robinson

The paper presents a large-scale corpus of standardized phenopackets for genomic diagnostics and discovery, curated from literature and useful for software testing and genotype-phenotype analysis.

Human Genetics and Genomics Advances · Oct 10, 2024Peer-reviewedGenetic & Genomic Medicine

The GA4GH Phenopacket schema: A computable representation of clinical data for precision medicine

Julius O.B. Jacobsen, Michael Baudis, Gareth S Baynam, Jacques Samuel Beckmann, Sergi Beltrán, Orion J. Buske, Tiffany J. Callahan, Christopher G. Chute, Mélanie Courtot, Daniel Daniš, Olivier Elemento, Andrea Essenwanger, Robert R. Freimuth, Michael A. Gargano, Tudor Groza, , Peter N. Robinson

The paper introduces the GA4GH Phenopacket schema to standardize the exchange of phenotypic data for precision medicine applications.

Nature Biotechnology · Jun 1, 2022Peer-reviewedGenetic & Genomic Medicine

An algorithmic framework for isoform-specific functional analysis

Guy Karlebach, Leigh Carmody, Jagadish Chandrabose Sundaramurthi, Elena Casiraghi, Peter Hansen, Justin Reese, Chris Mungall, Giorgio Valentini, Peter N. Robinson

The paper introduces isopret, an algorithm for predicting isoform-specific functions using RNA-seq data, and shows that expression and splicing regulate distinct biological functions.

bioRxiv · May 13, 2022 · PreprintBioinformatics

In silico and in vitro screening of FDA-approved drugs for potential repurposing against tuberculosis

Sridharan Brindha, Jagadish Chandrabose Sundaramurthi, Savariar Vincent, Devadasan Velmurugan, John Joel Gnanadoss

This study screens FDA-approved drugs for tuberculosis repurposing using in silico and in vitro methods, identifying lymecycline and cefpodoxime as active against drug-susceptible and resistant strains.

bioRxiv · Dec 3, 2017 · PreprintBioinformatics