Single-cell profiling of the human primary motor cortex in ALS and FTLD
Sergio Sebastian Pineda, Hyeseung Lee, Brent E. Fitzwalter, Shahin Mohammadi, Luc Pregent, Mahammad Gardashli, Julio C. Mantero, Erica Engelberg-Cook, Mariely DeJesus‐Hernandez, Marka van Blitterswijk, Cyril P. Pottier, Rosa Rademakers, Björn Oskarsson, Jaimin S. Shah, Ronald Carl Petersen, , Manolis Kellis
The paper creates a single-cell atlas of the human primary motor cortex in ALS and FTLD, identifying transcriptional changes and molecular similarities between Betz cells and VENs.
Cell · Mar 22, 2024Peer-reviewedNeuroscience