Author

Catharina Lange

Humboldt-Universität zu BerlinORCID 0000-0002-6745-8441Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:imaging· 3 Approach:deep learning· 2 Research Focus:benchmarking· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1 Approach:statistical model· 1

Frequent Co-Authors

Arina A. TagmazianiD· 2 shared Claudia SchwarziD· 2 shared Eero VuoksimaaiD· 2 shared Esa PitkäneniD· 2 shared for the Alzheimer’s Disease Neuroimaging Initiative· 1 shared Miranka WirthiD· 1 shared the Alzheimer’s Disease Neuroimaging Initiative· 1 shared the Frontotemporal Lobar Degeneration Neuroimaging Initiative· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 17 mutual co-author links

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2 shared papersBioinformatics

Arina A. TagmazianORCID

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3 papers

Recent·Most cited

petVAE: A Data-Driven Model for Identifying Amyloid PET Subgroups Across the Alzheimer's Disease Continuum

Arina A. Tagmazian, Claudia Schwarz, Catharina Lange, Esa Pitkänen, Eero Vuoksimaa, the Frontotemporal Lobar Degeneration Neuroimaging Initiative

petVAE identifies biologically meaningful subgroups along the Alzheimer's disease continuum using a deep learning model trained on amyloid PET scans.

bioRxiv · May 18, 2026 · PreprintBioinformatics

ArcheD, a residual neural network for prediction of cerebrospinal fluid amyloid-beta from amyloid PET images

Arina A. Tagmazian, Claudia Schwarz, Catharina Lange, Esa Pitkänen, Eero Vuoksimaa, the Alzheimer’s Disease Neuroimaging Initiative

ArcheD predicts cerebrospinal fluid amyloid-beta levels from amyloid PET images with strong correlation, showing distinct brain region contributions across AD stages.

European Journal of Neuroscience · Apr 4, 2024Peer-reviewedNeuroscience

Cortisol associated with hypometabolism across the Alzheimer’s disease spectrum

Miranka Wirth, Catharina Lange, Willem Huijbers, for the Alzheimer’s Disease Neuroimaging Initiative

This study finds higher plasma cortisol levels are associated with reduced brain glucose metabolism and gray matter volume in Alzheimer's disease and mild cognitive impairment patients.

bioRxiv · Jan 9, 2019Neuroscience