Eero Vuoksimaa

Predicting Alzheimer's disease phenotypes with aging clocks: an exploratory analysis

This study explores proteomic and epigenetic aging clocks as biomarkers for Alzheimer's disease phenotypes, finding proteomic clocks improve explained variance in cognitive and biomarker measures by up to 18%.

petVAE: A Data-Driven Model for Identifying Amyloid PET Subgroups Across the Alzheimer's Disease Continuum

petVAE identifies biologically meaningful subgroups along the Alzheimer's disease continuum using a deep learning model trained on amyloid PET scans.

Cerebral cortical structures linked to intelligence

This study identifies the dorsolateral prefrontal cortex as strongly linked to intelligence using large-scale MRI data and Mendelian randomization, with additional regions showing causal relationships.

Genome-wide analysis of social behaviour in context: a meta-regression approach across social domains, reporters and developmental stages

This study uses genome-wide meta-regression to analyze social behavior across different contexts, ages, and reporters, identifying six genetic loci and showing modest heritability.

A proteomic signature of healthspan

The paper develops a proteomic signature (HPS) to predict healthspan, showing it predicts mortality and age-related diseases better than other biological age measures.

ArcheD, a residual neural network for prediction of cerebrospinal fluid amyloid-beta from amyloid PET images

ArcheD predicts cerebrospinal fluid amyloid-beta levels from amyloid PET images with strong correlation, showing distinct brain region contributions across AD stages.

Genome-wide analyses of vocabulary size in infancy and toddlerhood: associations with Attention-Deficit/Hyperactivity Disorder and cognition-related traits

This study identifies genetic links between early vocabulary development and ADHD and cognition traits using genome-wide analyses.

Uncovering the Genetic Architecture of Broad Antisocial Behavior through a Genome-Wide Association Study Meta-analysis.

This study identifies genetic variants associated with antisocial behavior through a genome-wide association meta-analysis, finding significant links to FOXP2 and correlations with multiple health and behavioral traits.

Genetic Association Study of Childhood Aggression across raters, instruments and age

This study conducts a genome-wide association meta-analysis of childhood aggression across multiple raters, instruments, and ages, identifying genetic correlations with various traits but no genome-wide significant SNPs.

Genome-wide association study identifies 48 common genetic variants associated with handedness.

This study identifies 48 genetic variants associated with handedness using a large GWAS, highlighting polygenic nature and genetic links to neuropsychiatric traits.

DNA methylation signatures of aggression and closely related constructs: A meta-analysis of epigenome-wide studies across the lifespan

This paper identifies DNA methylation sites associated with aggression through a meta-analysis of epigenome-wide studies across different age groups and tissues.

Brain structure mediates the association between height and cognitive ability

The paper investigates whether cortical size mediates the association between height and cognitive ability using twin data.