Chemical Coverage of the Human Reactome
Haejin Angela Kwak, Lihua Liu, Claudia Tredup, Sandra Röhm, Panagiotis Prinos, Jark Böttcher, Matthieu Schapira
The paper assesses current chemical coverage of the human Reactome, finding that 3% of proteins are targeted by chemical probes, but they cover 53% of pathways due to pathway overlap.
bioRxiv · Apr 23, 2024 · PreprintBioinformatics