Multi-modal Disentanglement of Spatial Transcriptomics and Histopathology Imaging
Hassaan Maan, Zongliang Ji, Elliot Sicheri, Tiak Ju Tan, Alina Selega, Ricardo Gonzalez, Rahul G. Krishnan, Bo Wang, Kieran R. Campbell
This paper introduces SpatialDIVA, a method to disentangle spatial transcriptomics and histopathology imaging data, showing it outperforms baselines in variation separation and batch effect removal.
bioRxiv · Feb 19, 2025 · PreprintGenomics