Modeling Patient-Reported Pain Trajectories with Frequent Minimum and Maximum Scores
Yanxi Liu, Richard Edmund Harris, Daniel Joseph Clauw, Emine O. Bayman, Andrew Leroux, Martin A. Lindquist
The paper introduces a Bayesian beta-binomial mixed-effects model to analyze zero- and one-inflated patient-reported pain scores, showing improved fit and accuracy compared to existing methods.
bioRxiv · Sep 3, 2026 · PreprintBioinformatics