Author

David Lee Williams

Rush University Medical CenterORCID 0000-0002-6815-4909Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Abigail RulloiD· 1 shared An ZhangiD· 1 shared Brenna FlowersiD· 1 shared Francesco AngelucciiD· 1 shared Irida KastratiiD· 1 shared Keacha Chang· 1 shared Luke N. M. HardingiD· 1 shared Maurizio BocchettaiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

Abigail RulloORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Unravelling the anti-cancer mechanisms elicited by non-covalent thioredoxin reductase inhibitors for triple negative breast cancer therapy.

Abigail Rullo, Brenna Flowers, Keacha Chang, An Zhang, Valentina Z. Petukhova, Luke N. M. Harding, Sammy Y. Aboagye, Maurizio Bocchetta, Wei Qiu, David Lee Williams, Francesco Angelucci, Pavel A. Petukhov, Irida Kastrati

This study identifies non-covalent TXNRD inhibitors that block TNBC cell proliferation by depleting deoxynucleotides and inhibiting ribonucleotide reductase, challenging the pro-oxidant mechanism paradigm.

Redox Biology · Dec 20, 2025Peer-reviewedCancer Biology