MicrobiologybioRxivPreprint
Performance of Rilpivirine-Based Hydrophobic Tags and PROTACs Directed Against HIV-1 Reverse Transcriptase
Ferdinand K. Amanor, Garrett D. Clements, Rabia Khurshid…·Christina Ochsenbauer
The paper evaluates rilpivirine-based hydrophobic tags and PROTACs for HIV-1 RT degradation, finding that PEG4-Ad shows low nanomolar potency but limited efficacy against resistance mutations.
DOI 10.64898/2026.09.24.753933