Phosphorylation of a tumor-derived ASXL2 epitope remodels 1 peptide-HLA binding affinity and interaction dynamics
Jiahui Zhang, Lin Lv, Bairun Chen, Xinpei Yi
This study investigates how phosphorylation of an ASXL2 epitope affects peptide-HLA binding affinity and dynamics, revealing structural and conformational changes that could inform cancer immunotherapy.
bioRxiv · Mar 10, 2026 · PreprintBioinformatics