Xinpei Yi

PhosSight improves phosphoproteome identification by addressing acquisition biases in DDA and DIA, enhancing sensitivity and reducing missing values in cancer research.

This study investigates how phosphorylation of an ASXL2 epitope affects peptide-HLA binding affinity and dynamics, revealing structural and conformational changes that could inform cancer immunotherapy.

DeepRescore2 improves phosphopeptide identification using deep learning, leading to more phosphosites detected and new biological insights in liver cancer.

SEPepQuant improves protein isoform characterization in shotgun proteomics by addressing limitations in existing methods, identifying isoform-level regulation events, and enabling cross-study comparisons.