Author

Danai Georgia Topouza

Queen's UniversityORCID 0000-0002-6897-9281Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Qingling DuaniD· 2 shared Amanda M ZachariasiD· 1 shared Amirthagowri AmbalavananiD· 1 shared Ciara D O'ConnoriD· 1 shared Elinor SimonsiD· 1 shared Hanlin CheniD· 1 shared Helia GhazinejadiD· 1 shared Jihoon ChoiiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Qingling DuanORCID

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2 papers

Recent·Most cited

Epistatic SNP network analysis (ESNA): A scalable framework for genome-wide detection of higher-order genetic interactions

Y Zhang, Ming Han, Amirthagowri Ambalavanan, Danai Georgia Topouza, Zhi Yi Fang, Sara A Stickley, Shrey Anand, Stuart E. Turvey, Piush J. Mandhane, Elinor Simons, Theo J. Moraes, Padmaja Subbarao, Jihoon Choi, Qingling Duan

ESNA detects higher-order genetic interactions using genome-wide SNP data, identifying 914 SNP network modules associated with respiratory outcomes in children.

medRxiv · May 13, 2026 · PreprintGenetic & Genomic Medicine

Chronobiological rhythms control of site- and cell-specific miRNA and mRNA genes and networks across the central nervous system

Amanda M Zacharias, Ciara D O'Connor, Danai Georgia Topouza, Zhi Yi Fang, Helia Ghazinejad, Hanlin Chen, Qing Duan, Nader Ghasemlou

The paper identifies rhythmic mRNA and miRNA genes, networks, and co-expression pairs across CNS regions using high-dimensional data and provides a searchable resource for analysis.

bioRxiv · Sep 9, 2024 · PreprintNeuroscience