BioinformaticsJournal of Molecular BiologyPeer-reviewed
Dynamic Coupling and Entropy Changes in KRAS G12D Mutation: Insights into Molecular Flexibility, Allostery and Function
Aysima Hacisuleyman, Deniz Yüret, Burak Erman
This study uses molecular dynamics simulations to show how the G12D mutation in KRAS increases entropy and dynamic coupling, altering its conformational landscape and function.
5 citations