BioinformaticsProceedings of the National Academy of SciencesPeer-reviewed
Prediction and Design of Protease Enzyme Specificity Using a Structure-Aware Graph Convolutional Network
Changpeng Lu, Joseph H. Lubin, Vidur Sarma…·Sagar D. Khare
This paper introduces PGCN, a structure-aware graph convolutional network for predicting protease specificity and designing proteases, showing accurate predictions and successful experimental validation.