An Adeno-Associated Viral vector encoding Neurotrophin 3 injected into affected forelimb muscles modestly improves sensorimotor function after contusive mid-cervical spinal cord injury.
Jared D. Sydney-Smith, Vanessa Megaro, Aline Barroso Spejo, Lawrence David Falcon Moon
This study evaluates the therapeutic effects of AAV-NT3 injection in a rat model of cervical spinal cord injury, showing modest improvements in forelimb function but not normalization of hyperreflexia.
bioRxiv · Feb 24, 2021 · PreprintNeuroscience