Author

Moritz Hanke

Leibniz Institute for Prevention Research and Epidemiology - BIPSORCID 0000-0002-7135-2690Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1

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Research Focus:benchmarking· 1 Research Focus:gene regulatory network inference· 1 Research Focus:software / tool· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

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Ronja ForaitaiD· 1 shared Theresa Harten· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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1 shared paperBioinformatics

Ronja ForaitaORCID

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1 paper

Recent·Most cited

BioinformaticsPLoS Computational BiologyPeer-reviewedMar 6, 2026

ConNIS and labeling instability: new statistical methods for improving the detection of essential genes in TraDIS libraries

Moritz Hanke, Theresa Harten, Ronja Foraita

This paper introduces ConNIS, a statistical method for detecting essential genes in TraDIS data, showing it outperforms existing methods, especially in low-density libraries, and provides a data-driven approach for parameter setting.

DOI 10.1371/journal.pcbi.1013428

statistical modelgene regulatory network inference

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