Jo Knight

This paper identifies shared genetic risk factors between schizophrenia and 19 immune diseases, including three variants with pleiotropic effects and significant genetic correlations for several immune diseases.

This study identifies common genetic variants associated with pulmonary arterial hypertension risk and survival, focusing on HLA-DPA1/DPB1 and a SOX17 enhancer locus.

The paper uses GWAS summary statistics to identify enrichment of heritability in immune system annotations for Alzheimer’s and Parkinson’s diseases.

The paper introduces goldi, an R package for identifying ontological terms in text, using word matching and an acceptance function.

This study investigates whether immune gene variation contributes to schizophrenia by analyzing genome-wide association data, finding limited immune gene enrichment beyond the MHC region compared to five autoimmune diseases.

This study fine-maps 94 inflammatory bowel disease loci to identify 45 causal variants with high confidence, providing insights into their functional impacts on disease mechanisms.

This paper introduces a method using Gene Ontology and stratified false discovery rate to prioritize genes for GWAS of hippocampal volume in Alzheimer's Disease Neuroimaging Initiative data.