Analysis of follow-up data in large biobank cohorts: a review of methodology
Anastassia Kolde, Merli Koitmäe, Meelis Käärik, Märt Möls, Krista Fischer
This paper reviews methodological challenges in GWAS of biobank data with time-to-event outcomes, proposing a two-step martingale residual approach for efficient analysis.
Frontiers in Genetics · Jun 25, 2025Peer-reviewedGenomics