Author

Tolunay Beker Aydemir

Cornell UniversityORCID 0000-0002-7155-4110Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Approach:statistical model· 2 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Trista Lee Thorn· 3 shared Samuel Blake Mitchell· 2 shared Abigail A Glick· 1 shared Alexander Lu· 1 shared Camille Duchamp-SmithiD· 1 shared Courtney H. Ruggiero· 1 shared Harini SampathiD· 1 shared J Zou· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersPhysiology

Trista Lee Thorn

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Multiomics Approach to Regionally Profile Zinc-Driven Host-Gut Microbiome Interactions in the Intestinal Tract

Savita C Sastry, Samuel Blake Mitchell, Abigail A Glick, Trista Lee Thorn, Alexander Lu, Tolunay Beker Aydemir

This study uses a multiomics approach to examine how zinc deficiency affects host-gut microbiome interactions in mice, revealing region-specific changes in metabolism, immunity, and microbial diversity.

Current Developments in Nutrition · Jul 1, 2026Peer-reviewedPhysiology

Hepatic stearoyl-CoA desaturase-1 is specifically suppressed by dextran sodium sulfate but does not influence colitis sensitivity

Camille Duchamp-Smith, Natalie Burchat, Lakshmi Gayathri Pantula, Samuel Blake Mitchell, Tolunay Beker Aydemir, Harini Sampath

This study shows that DSS-induced colitis suppresses hepatic SCD1 without affecting colitis severity, and reveals lipid metabolism changes in the liver and plasma.

bioRxiv · Jun 2, 2026 · PreprintPhysiology

The Ins and Outs of Manganese: ZIP14 facilitates the efflux of excess manganese from the brain.

J Zou, Trista Lee Thorn, Z Wang, Y Wang, Tolunay Beker Aydemir

This study shows ZIP14 facilitates manganese efflux from the brain by relocalizing to the basolateral membrane in BBB endothelial cells, and its deletion causes Mn accumulation.

bioRxiv · Jul 2, 2025 · PreprintPhysiology

Intestine-specific deletion of metal transporter Zip14 (Slc39a14) causes brain manganese overload and locomotor defects of manganism

Tolunay Beker Aydemir, Trista Lee Thorn, Courtney H. Ruggiero, Marjory Pompilus, Marcelo Febo, Robert J. Cousins

This study shows that deleting ZIP14 in the intestine causes manganese overload in the brain and motor defects, highlighting its role in manganese excretion.

American Journal of Physiology-Gastrointestinal and Liver Physiology · Jan 31, 2020Peer-reviewedNeuroscience