Renchu Guan

This paper introduces SpaWeaver, a framework for robust spatial multi-omics integration using weak anchors, showing improved performance in handling real-world challenges and enabling new biological insights.

This paper introduces SpatialEx and SpatialEx+ frameworks to integrate spatial multi-omics data using histology as an anchor, achieving high-parameter co-profiling across tissue sections.

This paper develops ViraChron, a temporal foundation model for HBV evolution, enabling accurate sequence completion and analysis of ancient HBV genomes.