Author

Sani-e-Zehra Zaidi

University of KarachiORCID 0000-0002-7176-0328Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 4 Organism:human· 4 Approach:statistical model· 4 Assay:DNA methylation· 2 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Aisha SiddiqaiD· 4 shared Muhammad Ali MemoniD· 4 shared Sadia AjaziD· 4 shared Saleema Mehboob Ali· 4 shared Aiysha AbidiD· 2 shared Shagufta KhaliqiD· 2 shared Sadaf Firasat· 1 shared

Activity by Year

2021-2022 · peak 3/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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4 shared papersGenetic & Genomic Medicine

Aisha SiddiqaORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Germline Mutation Analysis in Sporadic Breast Cancer Cases with Clinical Correlations

Sadia Ajaz, Sani-e-Zehra Zaidi, Saleema Mehboob Ali, Aisha Siddiqa, Muhammad Ali Memon

The paper analyzes germline mutations in 84 sporadic breast cancer patients from Pakistan, finding 11.9% with mutations in BRCA1, BRCA2, and TP53, mostly truncating variants.

Frontiers in Genetics · Mar 9, 2022Peer-reviewedGenetic & Genomic Medicine

Absence of Glutathione S-Transferase Theta 1 Gene is Significantly Associated with Breast Cancer Susceptibility in Pakistani Population and Poor Overall Survival in Breast Cancer Patients: A Case-Control and Case Series Analysis

Sadia Ajaz, Sani-e-Zehra Zaidi, Saleema Mehboob Ali, Aisha Siddiqa, Muhammad Ali Memon, Sadaf Firasat, Aiysha Abid, Shagufta Khaliq

This study finds that the GSTT1-absent genotype is significantly associated with increased breast cancer risk and poorer overall survival in Pakistani patients.

Frontiers in Oncology · Dec 6, 2021Peer-reviewedGenetic & Genomic Medicine

E-cadherin Gene Promoter Hyper-methylation in Blood Samples from Breast Cancer Cases

Sadia Ajaz, Sani-e-Zehra Zaidi, Saleema Mehboob Ali, Aisha Siddiqa, Muhammad Ali Memon

The paper reports E-cadherin promoter hypermethylation in blood samples from breast cancer patients, indicating its potential role in metastasis and treatment selection.

medRxiv · Mar 30, 2021 · PreprintGenetic & Genomic Medicine

Independent and Combined Associations of 677C/T and 1298A/C Polymorphisms in the MTHFR gene with Breast Cancers in a South-Asian Population

Sadia Ajaz, Sani-e-Zehra Zaidi, Saleema Mehboob Ali, Aisha Siddiqa, Muhammad Ali Memon, Aiysha Abid, Shagufta Khaliq

The paper analyzes the associations of MTHFR SNPs 677C/T and 1298A/C with breast cancer risk in a South-Asian population, finding significant diplotype effects but no independent SNP associations.

medRxiv · Mar 13, 2021 · PreprintGenetic & Genomic Medicine