Xiaosheng Wang

Inferring phenotypes of single cells based on the expression profiles of phenotype-associated marker genes in bulks and single cells

The paper introduces ScPP, an algorithm that infers single-cell phenotypes using bulk and single-cell marker gene expression profiles, showing improved performance over existing methods.

Pathway enrichment-based unsupervised learning identifies novel subtypes of cancer-associated fibroblasts in pancreatic ductal carcinoma

The paper introduces a pathway-based clustering method for scRNA-seq data to identify novel subtypes of cancer-associated fibroblasts in pancreatic ductal carcinoma, showing distinct biological and clinical features.

Pan-cancer analysis reveals embryonic and hematopoietic stem cell signatures to distinguish different cancer subtypes

The paper identifies four pan-cancer subtypes based on embryonic and hematopoietic stem cell signatures, showing distinct clinical and molecular features and prognostic implications.

Defining Multiple Layers of Intratumor Heterogeneity Based on Variations of Perturbations in Multi-omics Profiling

The paper develops multi-omics ITH measures using information entropy across six molecular levels and shows their correlations with clinical outcomes and molecular regulatory relationships.

Malaria and Burkitt’s Lymphoma: An In Silico Analysis of Gene Expression Links between Malaria and Burkitt’s Lymphoma and Potential Anticancer Activity of Artemisinin Derivatives

The paper identifies molecular overlaps between malaria and Burkitt’s lymphoma and links artemisinin derivatives to shared pathways that could inform their anticancer potential.