Defining Multiple Layers of Intratumor Heterogeneity Based on Variations of Perturbations in Multi-omics Profiling
Hongjing Ai, Dandan Song, Xiaosheng Wang
The paper develops multi-omics ITH measures using information entropy across six molecular levels and shows their correlations with clinical outcomes and molecular regulatory relationships.
Computers in Biology and Medicine · Apr 19, 2023Peer-reviewedBioinformatics