Author

Stephen L. Mathias

University of New MexicoORCID 0000-0002-7255-370XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:GWAS summary statistics· 1 Organism:human· 1

Frequent Co-Authors

Cristian BologaiD· 2 shared Jeremy J. YangiD· 2 shared Lars Juhl JenseniD· 2 shared Tudor Ionel OpreaiD· 2 shared Ádám HalásziD· 1 shared Amar Koleti· 1 shared Anna WalleriD· 1 shared Caty Chung· 1 shared

Activity by Year

2017-2024 · peak 1/yr

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10 top collaborators · 30 mutual co-author links

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2 shared papersBioinformatics

Cristian BologaORCID

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3 papers

Recent·Most cited

Deep Learning enabled discovery of kinase drug targets in Pharos

Ádám Halász, Stephen L. Mathias, Srinjoy Das, Jeremy S. Edwards

The paper develops a deep learning framework to predict kinase-ligand interactions using molecular structure and Gene Ontology data from the Pharos database.

bioRxiv · Oct 8, 2024 · PreprintBioinformatics

TIGA: Target illumination GWAS analytics

Jeremy J. Yang, Dhouha Grissa, Christophe Gerard Lambert, Cristian Bologa, Stephen L. Mathias, Anna Waller, David J. Wild, Lars Juhl Jensen, Tudor Ionel Oprea

TIGA aggregates and ranks gene-trait associations from GWAS data to prioritize drug targets using statistical and bibliometric evidence.

Bioinformatics · Jun 3, 2021Peer-reviewedBioinformatics

Drug Target Ontology to Classify and Integrate Drug Discovery Data

Yu Lin, Saurabh Mehta, Hande Küçük‐McGinty, John Paul Turner, Dušica Vidović, Michele Forlin, Amar Koleti, Ðắc-Trung Nguyễn, Lars Juhl Jensen, Rajarshi Guha, Stephen L. Mathias, Oleg Ursu, Vasileios Stathias, Jianbin Duan, Nooshin Nabizadeh, , Stephan C. Schürer

The paper introduces the Drug Target Ontology (DTO) to classify and integrate drug discovery data by formalizing druggable protein targets and their characteristics.

Journal of Biomedical Semantics · Nov 9, 2017Peer-reviewedBioinformatics