Author

Kiran Krishnamachari

Agency for Science, Technology and ResearchORCID 0000-0002-7261-6811Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Anders J. SkanderupiD· 1 shared Anna GaniD· 1 shared Hanaé CarriéiD· 1 shared Iain Beehuat TaniD· 1 shared Limsoon WongiD· 1 shared Ngak Leng SimiD· 1 shared Polly S. Y. PooniD· 1 shared Pui‐Mun WongiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioinformatics

Anders J. SkanderupORCID

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1 paper

Recent·Most cited

Comprehensive benchmarking of methods for mutation calling in circulating tumor DNA

Hanaé Carrié, Ngak Leng Sim, Pui‐Mun Wong, Anna Gan, Yi Ting Lau, Polly S. Y. Poon, Saranya Thangaraju, Iain Beehuat Tan, Yoon Sim Yap, Kiran Krishnamachari, Limsoon Wong, Anders J. Skanderup

The paper benchmarks 9 somatic variant calling algorithms on cfDNA samples from cancer patients, identifying optimal methods based on ctDNA levels and sequencing depth.

Nature Communications · Dec 18, 2025Peer-reviewedBioinformatics