Author

Saranya Thangaraju

Agency for Science, Technology and ResearchORCID 0000-0003-4952-2902Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:whole-genome sequencing· 2 Research Focus:benchmarking· 1 Approach:deep learning· 1 Approach:machine learning (classical)· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Anders J. SkanderupiD· 2 shared Anna GaniD· 2 shared Hanaé CarriéiD· 2 shared Iain Beehuat TaniD· 2 shared Limsoon WongiD· 2 shared Ngak Leng SimiD· 2 shared Polly S. Y. PooniD· 2 shared Pui‐Mun WongiD· 2 shared

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2023-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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2 shared papersBioinformatics

Anders J. SkanderupORCID

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2 papers

Recent·Most cited

BioinformaticsNature CommunicationsPeer-reviewedDec 18, 2025

Comprehensive benchmarking of methods for mutation calling in circulating tumor DNA

Hanaé Carrié, Ngak Leng Sim, Pui‐Mun Wong…·Anders J. Skanderup

The paper benchmarks 9 somatic variant calling algorithms on cfDNA samples from cancer patients, identifying optimal methods based on ctDNA levels and sequencing depth.

2 citations

humanwhole-genome sequencing

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BioinformaticsbioRxivPreprintJul 28, 2023

Fragle: Universal ctDNA quantification using deep learning of fragmentomic profiles

Guanhua Zhu, Chowdhury Rafeed Rahman, Victor Getty…·Anders J. Skanderup

Fragle quantifies ctDNA from fragment length profiles using deep learning, showing high accuracy and improved detection limits across multiple datasets and sequencing types.

4 citations

humanwhole-genome sequencing

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