James D. Odum

Plasma regulates homeostatic pulmonary endothelial signaling to mitigate vascular leak following polytrauma and hemorrhagic shock

This study shows that fresh frozen plasma resuscitation after polytrauma and hemorrhagic shock reduces inflammation and preserves vascular barrier function by enhancing mitochondrial signaling and metabolic recovery in pulmonary endothelial cells.

Immunomodulatory Effects of a Cell Processing Device: Insights from Single Cell RNA Sequencing and Gene Set Enrichment Analysis

This study uses scRNA-seq to show SCD-treated monocytes have reduced pro-inflammatory gene expression and increased anti-inflammatory markers, suggesting a shift to a less inflammatory phenotype.