Author

Brenda Jane Smith

Indiana UniversityORCID 0000-0002-7296-8534Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 3

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Organism:mouse· 2 Research Focus:benchmarking· 1 Organism:human· 1

Frequent Co-Authors

Ashlee N. Ford VersyptiD· 3 shared Carley V. Cook· 2 shared Mohammad Aminul IslamiD· 2 shared Anna C. NelsoniD· 1 shared Ariel M. LightyiD· 1 shared Edwina YeoiD· 1 shared Lauryn Keeler BruceiD· 1 shared Pritha DuttaiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersSystems Biology

Ashlee N. Ford VersyptORCID

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3 papers

Recent·Most cited

Mathematical Modeling of Bone Remodeling after Surgical Menopause

Anna C. Nelson, Edwina Yeo, Yun Zhang, Carley V. Cook, Sophie Fischer-Holzhausen, Lauryn Keeler Bruce, Pritha Dutta, Samaneh Gholami, Brenda Jane Smith, Ashlee N. Ford Versypt

The paper develops a mathematical model to simulate bone remodeling after surgical menopause, showing increased bone loss initially and a long-term rebound in bone density.

Frontiers in Systems Biology · Feb 11, 2026Peer-reviewedSystems Biology

Mathematical Modeling of Estrogen-Mediated Inflammation in the Gut and Immune System

Ariel M. Lighty, Mohammad Aminul Islam, Brenda Jane Smith, Ashlee N. Ford Versypt

The paper develops a mathematical model to study how estrogen deficiency affects gut inflammation and immune cell dynamics, comparing predictions to in vivo mouse data.

bioRxiv · Dec 23, 2024 · PreprintSystems Biology

Mathematical modeling of the effects of Wnt-10b on bone metabolism

Carley V. Cook, Mohammad Aminul Islam, Brenda Jane Smith, Ashlee N. Ford Versypt

The paper models the effects of Wnt-10b on bone metabolism using differential equations and validated parameters from mouse data, predicting increased pre-osteoblasts and osteoblasts and decreased osteoclasts.

AIChE Journal · Jun 18, 2022Peer-reviewedSystems Biology