HPV status and oxygen tension shape transcriptomic, inflammatory, and cell cycle responses in HNSCC treated with ionizing radiation
Jana Pereckova, Filip Zavadil Kokas, Simona Voznicova, Ondřej Vašíček, Jitka Holčáková, Roman Hrstka, Tomáš Perečko
This study examines how HPV status and oxygen levels affect radiation response in HNSCC cell lines, showing differential gene expression, cytokine secretion, and cell cycle changes.
bioRxiv · Oct 26, 2025 · PreprintCancer Biology