Cross-Cancer Evaluation of Polygenic Risk Scores for 17 Cancer Types in Two Large Cohorts
Rebecca E. Graff, Taylor B. Cavazos, Khanh K. Thai, Linda Kachuri, Sara R. Rashkin, Joshua Hoffman, Stacey Alexeeff, Maruta A. Blatchins, Travis J. Meyers, Lancelote Leong, Caroline Gar-Ling Tai, Nima C. Emami, Douglas A. Corley, Lawrence H. Kushi, Elad Ziv, , Lori C. Sakoda
This study evaluates polygenic risk scores across 17 cancer types in two large cohorts, identifying cross-cancer associations and non-cancer phenotype links.
Nature Communications · Feb 12, 2021Peer-reviewedGenetics