Population-based mechanistic modeling allows for quantitative predictions of drug responses across cell types
Jingqi Q.X. Gong, Eric A. Sobie
The paper develops a cross-cell type regression model to predict drug responses in adult cardiac myocytes using iPSC-CM data, showing accurate predictions for both healthy and diseased cells.
npj Systems Biology and Applications · Feb 20, 2018Peer-reviewedSystems Biology