Author

Andrew J. Holmes

The University of SydneyORCID 0000-0002-7406-4387Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:ecology & biodiversity· 1 Assay:metabolomics· 1 Assay:metagenomics· 1

Frequent Co-Authors

Christina Jane AdleriD· 1 shared Dale David McClureiD· 1 shared Erin Rose ShanahaniD· 1 shared Fang WangiD· 1 shared Gina V. BrowneiD· 1 shared Juan Pablo Molina OrtiziD· 1 shared Kylie M. Davis· 1 shared Mark Norman ReadiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperEcology

Christina Jane AdlerORCID

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2 papers

Recent·Most cited

Ecological and evolutionary dynamics of the oral microbiome across childhood

Fang Wang, Andrew J. Holmes, Gina V. Browne, Xuzhen He, Michelle R. Bockmann, Kylie M. Davis, Toby E Hughes, Christina Jane Adler

The paper analyzes the oral microbiome's ecological and evolutionary changes across childhood using a twin cohort, finding host and environmental influences on microbial diversity and genetic variation.

bioRxiv · Feb 16, 2026 · PreprintEcology

Genome scale metabolic modelling of human gut microbes to inform rational community design

Juan Pablo Molina Ortiz, Dale David McClure, Andrew J. Holmes, Scott Alan Rice, Mark Norman Read, Erin Rose Shanahan

This study uses genome-scale metabolic models to design microbial communities that enhance butyrate production through DRC supplementation, showing improved resilience and intervention effectiveness.

Gut Microbes · Jul 20, 2025Peer-reviewedEcology