Author
Centre for Biomedical Network Research on Rare DiseasesORCID 0000-0002-7416-5137Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
4 papers
Recent·Most cited
George Jing Xu, Roshan A. Karunamuni, Anna M. Dornisch…·Tyler M. Seibert
This paper develops a germline polygenic score (PRSagg) to predict prostate cancer aggressiveness and validates it across multiple datasets.
Minh‐Phuong Huynh‐Le, Roshan A. Karunamuni, Chun Chieh Fan…·Canary PASS Investigators
The paper improves prostate cancer risk stratification across multiple ancestries using a new polygenic hazard score with additional SNPs, showing higher hazard ratios and positive predictive value for clinically significant prostate cancer.
UKGPCS collaborators, Roshan A. Karunamuni, APCB BioResource (Australian Prostate Cancer BioResource)…·Tyler M. Seibert
This study improves a polygenic hazard score for prostate cancer by adding 120 SNPs, enhancing hazard ratios but not positive predictive value of PSA testing.
Nicholas Mancuso, Simon A. Gayther, Alexander Gusev…·Peter Kraft
This study integrates a large prostate cancer GWAS with gene expression data to identify 235 genes associated with risk, prioritizing causal genes through Bayesian credible sets.