Optical pooled screening of a bacterial transposon mutagenesis library
Oscar Broström, Praneeth Karempudi, Elias Amselem, Maria Tenje, Johan Elf
The paper uses optical pooled screening to analyze a bacterial transposon mutagenesis library via live cell imaging, identifying mutants with replication initiation control perturbations in E. coli.
bioRxiv · Jul 7, 2026 · PreprintMicrobiology