Effect of Dual Leucine Zipper Kinase Inhibitor GNE-3511 on Epileptogenesis and Cognitive and Behavioral Changes in a Temporal Lobe Epilepsy Model in Mice
Dilan Acar, Emre Tunçcan, Serra Nur Selek, İrem Ekin Sayın, Can Berk Aşaroğlu, Gamze Tümentemur, Devrim Öz Arslan, Samet Özdemir, Güldal Güleç Süyen
This study investigates the effect of DLK inhibitor GNE-3511 on epilepsy and cognitive deficits in a mouse model, finding reduced seizures, anxiety, and neuronal loss.
bioRxiv · Jun 11, 2023 · PreprintNeuroscience