A spatially-specific pattern of cortical thickness in frontal lobe predisposes to faster future amyloid accumulation in individuals with subjective cognitive decline
Diego Vidaurre, Andrea Moreno, Óscar Sotolongo‐Grau, Pablo Oyarzo, Juan Pablo Tartari, Ángela Sanabria, Montserrat Alegret, Lluís Tárraga, Miren Jone Gurruchaga, Xavier Montalbán, Agustı́n Ruiz, Merçé Boada, Marta Marquié, Christopher Butler
The paper identifies a frontal lobe cortical thickness pattern in amyloid-negative individuals that predicts faster amyloid accumulation over five years.
bioRxiv · Jul 17, 2026 · PreprintNeuroscience