Author

Tanwee Alkutkar

Scripps Research InstituteORCID 0000-0002-7530-7424Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:Bayesian inference· 1 Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:phylogenetics / evolution· 1 Assay:protein structure· 1 Assay:scRNA-seq· 1 Research Focus:sequence-to-function modeling· 1 Approach:simulation· 1

Frequent Co-Authors

Andrew B. WardiD· 1 shared Armita NourmohammadiD· 1 shared Ashni A. VoraiD· 1 shared Chris Jennings-ShafferiD· 1 shared Duncan RalphiD· 1 shared Frederick A. Matsen IViD· 1 shared Gabriel D. VictoraiD· 1 shared Gabriel OzorowskiiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Andrew B. WardORCID

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1 paper

Recent·Most cited

ImmunologyCellPeer-reviewedJun 5, 2026

✦ In-depth digest

Replaying germinal center evolution on a quantified affinity landscape

William S. DeWitt, Ashni A. Vora, Tatsuya Araki…·Gabriel D. Victora

Across 119 monoclonal germinal centers, B cell affinity rises reliably despite divergent phylogenies. Selection is noisy but persistent; mutability limits exploration. A DMS-based landscape shows saturating fitness and survivorship biases.

30 citationstop 1%

mousescRNA-seq