Klemens J. Hertel

Interdependent regulation of alternative splicing by SR and hnRNP proteins

The paper analyzes the interdependent regulation of alternative splicing by SR and hnRNP proteins using computational methods on HepG2 and K562 cell datasets, revealing patterns of exon regulation and cell-type-specific differences.

The influence of 4-thiouridine labeling on pre-mRNA splicing outcomes

This study shows that 4-thiouridine labeling affects pre-mRNA splicing efficiency, particularly in introns with weak splice sites, and suggests the need for controls in labeling experiments.