Classical Myelo-Proliferative Neoplasms emergence and development based on real life incidence and mathematical modeling
Ana Fernández Baranda, Vincent Bansaye, Evelyne Lauret, Morgane Mounier, Valérie Ugo, Sylvie Méléard, Stéphane Giraudier
The paper uses mathematical modeling and real-world data to show that JAK2V617F mutations in MPNs emerge with age-dependent exponential rates and have distinct onset and expansion times between PV and ET.
bioRxiv · May 14, 2025 · PreprintCancer Biology