Immp2l knockdown increases stimulus-driven instrumental behaviour but does not alter goal-directed learning or neuron density in cortico-striatal circuits in a mouse model of Tourette syndrome and autism spectrum disorder
Beatrice K. Leung, Sam Merlin, Adam K. Walker, Adam J. Lawther, George Paxinos, Valsamma Eapen, Raymond A. Clarke, Bernard W. Balleine, Teri M. Furlong
This study investigates the effects of Immp2l knockdown in a mouse model of ASD and GTS, finding no impact on goal-directed learning or neuron density but increased stimulus-driven behaviour.
bioRxiv · Feb 12, 2023 · PreprintNeuroscience