Seyed Abolfazl Motahari

Large-Scale Assessment of the Iranian population structure of Mitochondrial and Y-chromosome Haplogroups

This study analyzes mitochondrial and Y-chromosome haplogroups in the Iranian population using whole-exome sequencing and SNP microarray data from 18,184 individuals, revealing patterns of genetic diversity and haplogroup distribution.

SureMap: Versatile, Error Tolerant, and High Sensitive Read Mapper

SureMap maps difficult reads with high sensitivity and error tolerance, identifying variants missed by other mappers and performing well on long, noisy reads.

Meta-aligner: Long-read alignment based on genome statistics

Meta-aligner improves long-read alignment accuracy and efficiency by using genome statistics, achieving higher recall for noisy reads.

GW-CALL: Accurate Genome-Wide Variant Caller

GW-CALL improves variant calling by using all reads, including those mappable to multiple locations, to enhance accuracy in repeat regions.

Breaking Lander-Waterman’s Coverage Bound

This paper improves the Lander-Waterman coverage bound by combining sequencing and computing processes, reducing the required sequenced bases from O(G ln G) to O(G).