Author

Takayoshi Sasako

Jewish General HospitalORCID 0000-0002-7644-309XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Approach:benchmark study· 1 Research Focus:differential expression· 1 Research Focus:fine-mapping· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Guillaume Butler‐LaporteiD· 2 shared Kevin Y. H. LiangiD· 2 shared Bangli Cao· 1 shared Celia M.T. GreenwoodiD· 1 shared Chen‐Yang SuiD· 1 shared Claudia LangenbergiD· 1 shared Dandan Tan· 1 shared John Brent RichardsiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Guillaume Butler‐LaporteORCID

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2 papers

Recent·Most cited

Disentangling osteoarthritis-specific genetic effects from obesity to identify novel therapeutic targets

Chen‐Yang Su, Masashi Hasebe, Dandan Tan, Bangli Cao, Kevin Y. H. Liang, Takayoshi Sasako, Vincent Mooser, Wenmin Zhang, Sirui Zhou, Satoshi Yoshiji, Tianyuan Lu, Guillaume Butler‐Laporte

This study identifies OA-specific genetic effects and novel therapeutic targets by separating OA genetics from those shared with obesity using GWAS and proteomics data.

medRxiv · Sep 23, 2025 · PreprintGenetic & Genomic Medicine

The performance of AlphaMissense to identify genes causing disease

Yiheng Chen, Guillaume Butler‐Laporte, Kevin Y. H. Liang, Yann Ilboudo, Summaira Yasmeen, Takayoshi Sasako, Claudia Langenberg, Celia M.T. Greenwood, John Brent Richards

This study evaluates AlphaMissense's impact on gene-based testing for disease causation using UK Biobank exome data, finding no significant improvement in identifying disease-causing genes.

medRxiv · Mar 5, 2024 · PreprintGenetic & Genomic Medicine