Metabolic enzyme cost explains variable trade-offs between microbial growth rate and yield
Meike Tessa Wortel, Εlad Noor, Michael C. Ferris, Frank J. Bruggeman, Wolfram Liebermeister
The paper uses EFCM to show growth rate/yield trade-offs in E. coli depend on metabolic kinetics and environmental conditions, with oxygen limitation favoring faster but less efficient growth.
PLoS Computational Biology · Feb 16, 2018Peer-reviewedSystems Biology