Meike Tessa Wortel

Additive effects of environmental and demographic variation shape the repeatability of evolution across replicated experiments

This study shows that environmental and demographic variation additively reduce the repeatability of evolution in replicated experiments with Caenorhabditis elegans.

A bifidobacterial enzyme orchestrates ecology and function of infant gut bacterial community

This study shows how a single bacterial enzyme, D4BMY8, influences the composition and metabolism of an infant gut microbial community through its preference for the HMO lacto-N-tetraose.

Environmentally mediated interactions predict community assembly and invasion success in a gut microbiota SynCom

This study uses a synthetic gut microbiota community to predict invasion success and community stability by modeling interactions between species.

A modular model integrating metabolism, growth, and cell cycle predicts that fermentation is required to modulate cell size in yeast populations

The paper develops a multiscale computational model integrating metabolism, growth, and cell cycle in yeast to predict that fermentation modulates cell size under different growth conditions.

Progression of ampC amplification during de novo amoxicillin resistance development in E. coli

This study tracks ampC amplification and promoter mutations during de novo amoxicillin resistance development in E. coli, showing amplification occurs after promoter mutations and is facilitated by IS1 transposition.

Metabolic enzyme cost explains variable trade-offs between microbial growth rate and yield

The paper uses EFCM to show growth rate/yield trade-offs in E. coli depend on metabolic kinetics and environmental conditions, with oxygen limitation favoring faster but less efficient growth.